Unlike textbooks that emphasize the memorization of facts, Asking Questions About Cultural Anthropology: A Concise Introduction, Third Edition, teaches students how to think anthropologically, helping them view cultural issues as an anthropologist might. This approach demonstrates how anthropological thinking can be used as a tool for deciphering everyday experiences. The book covers the essential concepts, terms, and history of cultural anthropology, introducing students to the widely accepted fundamentals and providing a foundation that can be enriched by the use of ethnographies, a reader, articles, lectures, field-based activities, and other kinds of supplements. It balances concise coverage of essential content with a commitment to an active, learner-centered pedagogy.

What is cultural anthropology, and how can it explain--or even help resolve--contemporary human problems? Robert L. Welsch and Luis A. Vivanco's Cultural Anthropology: Asking Questions About Humanity, Third Edition, uses a questions-based approach to teach students how to think anthropologically, helping them view cultural issues and everyday experiences as an anthropologist might. Inspired by the common observation that ninety-nine percent of a good answer is a good question, Cultural Anthropology combines a question-centered pedagogy with the topics typically covered in an introductory course. It emphasizes up front what the discipline of anthropology knows and which issues are in debate, and how a cultural perspective is relevant to understanding social, political, and economic dynamics in the contemporary world. Cultural Anthropology also represents an effort to close the gap between the realities of the discipline today and traditional views that are taught at the introductory level by bringing classic anthropological examples, cases, and analyses to bear on contemporary questions.

Routledge Companion to Cycling presents a comprehensive overview of an artefact that throughout the modern era has been a bellwether indicator of the major social, economic and environmental trends that have permeated society The volume synthesizes a rapidly growing body of research on the bicycle, its past and present uses, its technological evolution, its use in diverse geographical settings, its aesthetics and its deployment in art and literature. From its origins in early modern carriage technology in Germany, it has generated what is now a vast, multi-disciplinary literature encompassing a wide range of issues in countries throughout the world.

The book features photos of interiors, private houses, and restaurants, with the common thread of decorative ceilings, Gregory Gatserelia's signature.

In cities throughout the world, bicycles have gained a high profile in recent years, with politicians and activists promoting initiatives like bike lanes, bikeways, bike share programs, and other social programs to get more people on bicycles. Bicycles in the city are, some would say, the wave of the future for car-choked, financially-strapped, obese, and sustainability-sensitive urban areas. This book explores how and why people are reconsidering the bicycle, no longer thinking of it simply as a toy or exercise machine, but as a potential solution to a number of contemporary problems. It focuses in particular on what reconsidering the bicycle might mean for everyday practices and politics of urban mobility, a concept that refers to the intertwined physical, technological, social, and experiential dimensions of human movement. This book is for Introductory Anthropology, Cultural Anthropology, Cultural Sociology, Environmental Anthropology, and all undergraduate courses on the environment and on sustainability throughout the social sciences.

Ascorbic acid (AsA), vitamin C, is one of the most abundant water-soluble antioxidant in plants and animals. In plants AsA serves as a major redox buffer and regulates various physiological processes controlling growth, development, and stress tolerance. Recent studies on AsA homeostasis have broadened our understanding of these physiological events. At the mechanistic level, AsA has been shown to participate in numerous metabolic and cell signaling processes, and the dynamic relationship between AsA and reactive oxygen species (ROS) has been well documented. Being a major component of the ascorbate-glutathione (AsA-GSH) cycle, AsA helps to modulate oxidative stress in plants by controlling ROS detoxification alone and in co-operation with glutathione. In contrast to the single pathway responsible for AsA biosynthesis in animals, plants utilize multiple pathways to synthesize AsA, perhaps reflecting the importance of this molecule to plant health. Any fluctuations, increases or decreases, in cellular AsA levels can have profound effects on plant growth and development, as AsA is associated with the regulation of the cell cycle, redox signaling, enzyme function and defense gene expression. Although there has been significant progress made investigating the multiple roles AsA plays in stress tolerance, many aspects of AsA-mediated physiological responses require additional research if AsA metabolism is to be manipulated to enhance stress-tolerance. This book summarizes the roles of AsA that are directly or indirectly involved in the metabolic processes and physiological functions of plants. Key topics include AsA biosynthesis and metabolism, compartmentation and transport, AsA-mediated ROS detoxification, as well as AsA signaling functions in plant growth, development and responses to environmental stresses. The main objective of this volume is therefore to supply comprehensive and up-to-date information for students, scholars and scientists interested in or currently engaged in AsA research.

Glutathione ( -glutamyl-cysteinyl-glycine) is a ubiquitously distributed sulfurcontaining antioxidant molecule that plays key roles in the regulation of plant growth, development, and abiotic and biotic stress tolerance. It is one of the most powerful low-molecular-weight thiols, which rapidly accumulates in plant cells under stress. Recent in-depth studies on glutathione homeostasis (biosynthesis, degradation, compartmentalization, transport, and redox turnover) and the roles of glutathione in cell proliferation and environmental stress tolerance have provided new insights for plant biologists to conduct research aimed at deciphering the mechanisms associated with glutathione-mediated plant growth and stress responses, as well as to develop stress-tolerant crop plants. Glutathione has also been suggested to be a potential regulator of epigenetic modifications, playing important roles in the regulation of genes involved in the responses of plants to changing environments. The dynamic relationship between reduced glutathione (GSH) and reactive oxygen species (ROS) has been well documented, and glutathione has been shown to participate in several cell signaling and metabolic processes, involving the synthesis of protein, the transport of amino acids, DNA repair, the control of cell division, and programmed cell death. Two genes, gamma-glutamylcysteine synthetase (GSH1) and glutathione synthetase (GSH2), are involved in GSH synthesis, and genetic manipulation of these genes can modulate cellular glutathione levels. Any fluctuations in cellular GSH and oxidized glutathione (GSSG) levels have profound effects on plant growth and development, as glutathione is associated with the regulation of the cell cycle, redox signaling, enzymatic activities, defense gene expression, systemic acquired resistance, xenobiotic detoxification, and biological nitrogen fixation. Being a major constituent of the glyoxalase system and ascorbate-glutathione cycle, GSH helps to control multiple abiotic and biotic stress signaling pathways through the regulation of ROS and methylglyoxal (MG) levels. In addition, glutathione metabolism has the potential to be genetically or biochemically manipulated to develop stress-tolerant and nutritionally improved crop plants. Although significant progress has been made in investigating the multiple roles of glutathione in abiotic and biotic stress tolerance, many aspects of glutathione-mediated stress responses require additional research. The main objective of this volume is to explore the diverse roles of glutathione in plants by providing basic, comprehensive, and in-depth molecular information for advanced students, scholars, teachers, and scientists interested in or already engaged in research that involves glutathione. Finally, this book will be a valuable resource for future glutathione-related research and can be considered as a textbook for graduate students and as a reference book for frontline researchers working on glutathione metabolism in relation to plant growth, development, stress responses, and stress tolerance.

The use of proteomics to study complex diseases such as cardiovascular disease, the leading cause of death in developed countries, has grown exponentially in recent years. Proteomics is a rapidly expanding investigation platform in cardiovascular medicine and is becoming integrated and incorporated into cardiovascular research. The proteomics field continues to develop with major improvements in mass spectrometry instrumentation, methodology and data analysis. Heart Proteomics: Methods and Protocols complies a selection of techniques and methods that target the numerous processes implicated in the pathophysiology of heart. Chapters cover protocols and updated methods in the heart proteomic area with a particular focus on MS-based methods of protein and peptide quantification and the analysis of posttranslational modifications as well as descriptions of system biology approaches, which provide a better understanding of normal and pathological processes. Written in the successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Heart Proteomics: Methods and Protocols is a representative selection of methods that will prove to be a useful resource for experienced proteomics practitioners and newcomers alike.

Proteomics is a rapidly expanding investigation platform in cardiovascular medicine. Driven by major improvements in mass spectrometry (MS) instrumentation and data analysis, the proteomics field has flourished in recent years particularly in the study of complex diseases. These recent advances are characterized by the development of quantitative MS-based methods that promoted the field from primarily identifying proteins to also providing measurements of relative changes in protein levels between different cell states. This progress is reflected in the application of proteomic techniques to vascular pathology. Vascular Proteomics: Methods and Protocols provides up-to-date methods and protocols for the analysis of arteries, cells, lipoproteins, body fluids, and metabolites, with a particular focus on MS-based methods of protein and peptide quantification. Written in the successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Vascular Proteomics: Methods and Protocols is a representative selection of methods that can be a useful resource for experienced proteomics practitioners as well as newcomers interested in becoming acquainted with the practice of proteomic techniques for cardiovascular research.

The identification of normal and breast cancer stem cells has offered a new vision of this heterogeneous disease and new hopes for its prognosis and treatment. This volume provides an overview of recent developments in mammary stem cell research and discusses the many varieties of approaches used by researchers to investigate the properties and functions of mammary stem cells. The beginning chapters provide readers with an introduction to mammary stem cells, and the processes used to characterize stem cells and isolate them via fluorescent activated cell sorting. The next few chapters discuss DNA and mRNA sequencing, proteomic techniques to help profile cells, lentiviral cell transduction for gene expression, and in vivo lineage tracing. The final few chapters are dedicated to following stem cells from their initial niche to the new microenvironment at their metastasis site, and to studying these cells using physical and mathematical approaches. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and cutting-edge, Mammary Stem Cells: Methods and Protocols aims to help members of the scientific community explore the behavior of stem cells and how to work with them in order to guide the design of new and complimentary strategies to be applied in the clinic with the ultimate end goal of fighting breast cancer.

Secretions and emissions in biological systems play important signaling roles within the organism but also in its communications with the surrounding environment. This volume brings together state-of-the-art information on the role of secretions and emissions in different organs and organisms ranging from flowers and roots of plants to nematodes and human organs. The plant chapters relate information regarding the biochemistry of flower volatiles and root exudates, and their role in attracting pollinators and soil microbial communities respectively. Microbial chapters explain the biochemistry and ecology of quorum sensing and how microbial communities highly co-adapted to plants can aid in bio-energy applications by degrading ligno-cellulosic materials. Other chapters explain the biology of secretions by nematodes, algae and humans, among other organisms. This volume will be a welcome addition to the literature, as no other book covers aspects related to biological secretion in such a holistic and integrative manner.

Offering a transdisciplinary analysis of works by Gloria Anzaldua, Cherrie Moraga, Ana Castillo, Emma Perez, Alicia Gaspar de Alba, and Sandra Cisneros, this book explores how radical Chicanas deal with tensions that arise from their focus on the body, desire, and writing.

In "This Bridge Called My Back," Gloria Anzaldua wrote: "A woman who writes has power. A woman who writes is feared. In the eyes of the world this makes us dangerous beasts." Her statement marked a moment of collective self-recognition. "Radical Chicana Poetics" considers this moment as a point of entry into Chicana writings. Offering a transdisciplinary analysis of works by Anzaldua, Cherrie Moraga, Ana Castillo, Emma Perez, Alicia Gaspar de Alba, and Sandra Cisneros, this book explores how radical Chicanas deal with tensions that arise from their focus on the body, desire, and writing. Delving into the subtle differences between the authors, Ricardo F. Vivancos Perez sheds new light on contemporary cultural production and feminist activism, and reflects upon positionality and ethics in Chican@ and Latin@ scholarship.

The mystique of the rainforest has captured the imaginations of generations of young people, explorers, authors, and biologists. It is a delicate ecosystem whose myriad sounds and smells, whose vibrancy of life, is balanced by constant cycles of death and decay. It is a place of fierce competition where unusual partnerships are forged and creative survival strategies are the norm. In this book, you will meet the scientific pioneers who first attempted to quantify and understand the vast diversity of these tropical forests, as well as their successors, who utilize modern tools and technologies to dissect the chemical nature of rainforest interactions.

This book provides a general background on biodiversity and the study of chemical ecology before moving into specific chemical examples of insect defenses and microbial communication. It finishes with first-hand accounts of the trials and tribulations of a canopy biology pioneer and a rainforest research novice, while assessing the state of modern tropical research, its importance to humanity, and the ecological, political, and ethical issues that need to be tackled in order to move the field forward.

The use of proteomics to study complex diseases such as cardiovascular disease, the leading cause of death in developed countries, has grown exponentially in recent years. Proteomics is a rapidly expanding investigation platform in cardiovascular medicine and is becoming integrated and incorporated into cardiovascular research. The proteomics field continues to develop with major improvements in mass spectrometry instrumentation, methodology and data analysis. Heart Proteomics: Methods and Protocols complies a selection of techniques and methods that target the numerous processes implicated in the pathophysiology of heart. Chapters cover protocols and updated methods in the heart proteomic area with a particular focus on MS-based methods of protein and peptide quantification and the analysis of posttranslational modifications as well as descriptions of system biology approaches, which provide a better understanding of normal and pathological processes. Written in the successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Heart Proteomics: Methods and Protocols is a representative selection of methods that will prove to be a useful resource for experienced proteomics practitioners and newcomers alike.

Proteomics is a rapidly expanding investigation platform in cardiovascular medicine. Driven by major improvements in mass spectrometry (MS) instrumentation and data analysis, the proteomics field has flourished in recent years particularly in the study of complex diseases. These recent advances are characterized by the development of quantitative MS-based methods that promoted the field from primarily identifying proteins to also providing measurements of relative changes in protein levels between different cell states. This progress is reflected in the application of proteomic techniques to vascular pathology. Vascular Proteomics: Methods and Protocols provides up-to-date methods and protocols for the analysis of arteries, cells, lipoproteins, body fluids, and metabolites, with a particular focus on MS-based methods of protein and peptide quantification. Written in the successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Vascular Proteomics: Methods and Protocols is a representative selection of methods that can be a useful resource for experienced proteomics practitioners as well as newcomers interested in becoming acquainted with the practice of proteomic techniques for cardiovascular research.

Secretions and emissions in biological systems play important signaling roles within the organism but also in its communications with the surrounding environment. This volume brings together state-of-the-art information on the role of secretions and emissions in different organs and organisms ranging from flowers and roots of plants to nematodes and human organs. The plant chapters relate information regarding the biochemistry of flower volatiles and root exudates, and their role in attracting pollinators and soil microbial communities respectively. Microbial chapters explain the biochemistry and ecology of quorum sensing and how microbial communities highly co-adapted to plants can aid in bio-energy applications by degrading ligno-cellulosic materials. Other chapters explain the biology of secretions by nematodes, algae and humans, among other organisms. This volume will be a welcome addition to the literature, as no other book covers aspects related to biological secretion in such a holistic and integrative manner.

The mystique of the rainforest has captured the imaginations of generations of young people, explorers, authors, and biologists. It is a delicate ecosystem whose myriad sounds and smells, whose vibrancy of life, is balanced by constant cycles of death and decay. It is a place of fierce competition where unusual partnerships are forged and creative survival strategies are the norm. In this book, you will meet the scientific pioneers who first attempted to quantify and understand the vast diversity of these tropical forests, as well as their successors, who utilize modern tools and technologies to dissect the chemical nature of rainforest interactions.

This book provides a general background on biodiversity and the study of chemical ecology before moving into specific chemical examples of insect defenses and microbial communication. It finishes with first-hand accounts of the trials and tribulations of a canopy biology pioneer and a rainforest research novice, while assessing the state of modern tropical research, its importance to humanity, and the ecological, political, and ethical issues that need to be tackled in order to move the field forward.

"Vivanco's well-written work clearly raises important questions regarding whether or not ecotourism can overcome the ecological and social equity challenges of sutainable development." - Choice "The work excels at showing how environmental conservation oat Monte Verde is and has been the result of a shifting range of social, political, and economic forces, and it also excels at showing the variety of environmentalisms that can be found there." - JRAI Since the 1970s and 1980s, Monte Verde, Costa Rica has emerged as one of the most renowned sites of nature conservation and ecotourism in Costa Rica, and some would argue, Latin America. It has received substantial attention in literature and media on tropical conservation, sustainable development, and tourism. Yet most of that analysis has uncritically evaluated the Monte Verde phenomenon, using celebratory language and barely scratching the surface of the many-faceted socio-cultural transformations provoked by and accompanying environmentalism. Because of its stature, Monte Verde represents an ideal case study to examine the socio-cultural and political complexities and dilemmas of practicing environmentalism in rural Costa Rica. Based on many years of close observation, this book offers rich and original material on the ongoing struggles between environmental activists and of collective and oppositional politics to Monte Verde's new "culture of nature." Luis A. Vivanco is Assistant Professor of Anthropology at the University of Vermont (1999-present). He received a Ph.D. in Cultural Anthropology from Princeton University. He is co-editor of Tarzan was an Ecotourist...and Other Tales in the Anthropology of Adventure (Berghahn Books, 2006). He is a co-editor of Talking About People: Readings in Contemporary Cultural Anthropology (McGraw Hill). His research focuses on the culture and politics of nature conservation, ecotourism, and sustainable development in Costa Rica and Oaxaca, Mexico.

Cardiovascular Proteomics: Methods and Protocols presents cutting-edge protocols and strategies for proteomic evaluation of cardiovascular disease written by pioneering researchers in the field. Topics explored in this comprehensive volume include obtaining specific heart proteins, cutting-edge techniques for identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, and phage display techniques for deciphering the molecular diversity of blood vessels. Detailed protocols for the isolation of short- and long-term culture of the adult mouse cardiac myocytes are also included.

Numerous advanced proteomic techniques are addressed, including protein separation by two-dimensional electrophoresis and two-dimensional difference gel electrophoresis, liquid chromatography coupled to mass spectrometry, and the SELDI-TOF approach to searching for biomarkers of stroke in human serum or of hypertension in the serum of animal models. Proteomic strategies and protocols for studying the proteome of endothelial, arterial smooth muscle cells, foam cells, and circulating blood monocytes constitute a major element of this text. Cutting-edge techniques for the analysis of subproteomes from isolation to final characterization and the characterization of posttranslational modifications are also addressed. This useful snapshot of current proteomic techniques is a single source for protocols for the identification and validation of novel biomarkers and targets in cardiovascular diseases.

Adventure is currently enjoying enormous interest in public culture. The image of Tarzan provides a rewarding lens through which to explore this phenomenon. In their day, Edgar Rice Burrough's novels enjoyed great popularity because Tarzan represented the consummate colonial-era adventurer: a white man whose noble civility enabled him to communicate with and control savage peoples and animals. The contemporary Tarzan of movies and cartoons is in many ways just as popular, but carries different connotations. Tarzan is now the consummate "eco-tourist:" a cosmopolitan striving to live in harmony with nature, using appropriate technology, and helpful to the natives who cannot seem to solve their own problems. Tarzan is still an icon of adventure, because like all adventurers, his actions have universal qualities: doing something previously untried, revealing the previously undiscovered, and experiencing the unadulterated. Prominent anthropologists have come together in this volume to reflect on various aspects of this phenomenon and to discuss contemporary forms of adventure.

Since the 1970s and 1980s, Monte Verde, Costa Rica has emerged as one of the most renowned sites of nature conservation and ecotourism in Costa Rica, and some would argue, Latin America. It has received substantial attention in literature and media on tropical conservation, sustainable development, and tourism. Yet most of that analysis has uncritically evaluated the Monte Verde phenomenon, using celebratory language and barely scratching the surface of the many-faceted socio-cultural transformations provoked by and accompanying environmentalism. Because of its stature, Monte Verde represents an ideal case study to examine the socio-cultural and political complexities and dilemmas of practicing environmentalism in rural Costa Rica. Based on many years of close observation, this book offers rich and original material on the ongoing struggles between environmental activists and of collective and oppositional politics to Monte Verde's new 'culture of nature.'

This second edition provides an overview of recent developments and approaches used by researchers to investigate the properties and functions of mammary epithelial and stem cells, which will contribute to understand the heterogeneity of the mammary gland and of breast cancer. Chapters detail processes used to characterize stem cells, single cell RNA sequencing, computational methods, sophisticated imaging techniques, and a variety of model systems, among others. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mammary Stem Cells: Methods and Protocols, Second Edition aims to make available protocols used to navigate the intricate behavior of mammary stem cells and to gain further knowledge to take us closer to the design of innovative strategies to prevent and treat breast cancer.

This general anthropology text takes a holistic approach that emphasizes critical thinking, active learning, and applying anthropology to solve contemporary human problems. Building on the classical foundations of the discipline, Anthropology: Asking Questions About Human Origins, Diversity, and Culture, Second Edition, shows students how anthropology is connected to such current topics as food, health and medicine, and the environment. Full of relevant examples and current topics--with a focus on contemporary problems and questions--the book demonstrates the diversity and dynamism of anthropology today.

"An important strength of this collection is the ethnographic grounding of the chapters, which directly engage rich ethnographic understandings with Simmel's work. This book is a useful addition to the anthropological literature on travel and tourism, and it is a pleasurable adventure to read." . American Anthropologist Adventure is currently enjoying enormous interest in public culture. The image of Tarzan provides a rewarding lens through which to explore this phenomenon. In their day, Edgar Rice Burrough's novels enjoyed great popularity because Tarzan represented the consummate colonial-era adventurer: a white man whose noble civility enabled him to communicate with and control savage peoples and animals. The contemporary Tarzan of movies and cartoons is in many ways just as popular, but carries different connotations. Tarzan is now the consummate "eco-tourist: " a cosmopolitan striving to live in harmony with nature, using appropriate technology, and helpful to the natives who cannot seem to solve their own problems. Tarzan is still an icon of adventure, because like all adventurers, his actions have universal qualities: doing something previously untried, revealing the previously undiscovered, and experiencing the unadulterated. Prominent anthropologists have come together in this volume to reflect on various aspects of this phenomenon and to discuss contemporary forms of adventure. Luis Vivanco is Assistant Professor of Anthropology at the University of Vermont. His research focuses on the cultural politics of environmentalism and ecotourism in Latin America. He is author of Green Encounters: Shaping and Contesting Environmentalism in Rural Costa Rica (Berghahn Books, 2006). Robert Gordon is Professor of Anthropology at the University of Vermont. He is author of numerous books and articles, including The Bushman Myth: The Making of a Namibian Underclass and Picturing Bushmen: The Denver African Expedition of 1925.